Tunable supramolecular assembly has found various applications in biomedicine, molecular catalysis, optoelectronics, and nanofabrication. Unlike traditional covalent conjugation, non‐covalent introduction of a photoswitchable moiety enables reversible photomodulation of non‐photosensitive dipeptide supramolecular assembly. Under light illumination, a long‐lived photoacid generator releases a proton and mediates the dissociation of dipeptide‐based organogel, thereby resulting in sol formation. Under darkness, the photoswitchable moiety entraps a proton, resulting in gel regeneration. Furthermore, accompanying the isothermal recycled gel–sol transition in a spatially controlled manner, renewable patterns are spontaneously fabricated. This new concept of light‐controlled phase transition of amino acid‐based supramolecular assemblies will open up the possibility of wide applications.

中文翻译：

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二肽超分子组装中的光诱导可逆相变。

可调谐的超分子组装已在生物医学，分子催化，光电子学和纳米制造中找到了各种应用。与传统的共价缀合不同，光交换部分的非共价引入可实现非光敏二肽超分子组装的可逆光调制。在光照下，寿命长的光致产酸剂释放质子并介导基于二肽的有机凝胶的解离，从而导致溶胶形成。在黑暗中，可光转换部分捕获质子，导致凝胶再生。此外，伴随以空间受控方式进行的等温循环凝胶-溶胶转变，可自发地制造出可再生的图案。