In Reply We thank Parikh for his excellent points and deeply appreciate his efforts to refine advanced magnetic resonance imaging (MRI) biomarkers toward multivariable prediction models in high-income contexts.

Our clinical practice guideline¹ was developed from the combined body of best-available evidence, sourced using a systematic review method, and organized by panel consensus using the GRADE framework. We did not review single articles in isolation to avoid selection and reporting bias. Furthermore, we examined multiple causal pathways to cerebral palsy, not just the preterm population as cited by Parikh, which affects the denominator value used for interpreting data.

在答复中，我们感谢Parikh的出色表现，并深切感谢他为在高收入情况下将高级磁共振成像（MRI）生物标记物改进为多变量预测模型所做的努力。

我们的临床实践指南¹是从最佳证据的合并体中得出的，使用系统的审查方法获得，并通过小组共识使用GRADE框架进行组织。我们没有单独审查单个文章，以避免选择和报告偏见。此外，我们检查了多种导致脑瘫的因果途径，而不仅仅是Parikh引用的早产人群，这会影响用于解释数据的分母值。