The copper (I) mediated tandem reaction of A³ coupling followed by a [3 + 2] cycloaddition methodology is developed for the first synthesis of structurally interesting 3-aryl/alkyl/silyl-4-amino-4H-[1,2,3]triazolo[1,5-a]indoles from various 2-azidobenzaldehydes, secondary amines, and terminal alkynes. The optimal reaction conditions of this one-pot tandem reaction are simple, performed at room temperature, and produce the corresponding products with high yields (up to 84%). The intermolecular [3 + 2] cycloaddition of 2-azidobenzaldehydes and terminal alkynes is found to be the competitive reaction for the presently developed tandem reaction with 2-triazole benzaldehydes as the minor products. The latter were also isolated and characterized.

开发了铜（I）介导的A ³偶联串联反应，然后是[3 ​​+ 2]环加成方法，用于首次合成结构上令人感兴趣的3-芳基/烷基/甲硅烷基-4-氨基-4 H- [1,2 ，3-]三唑并[1,5- a ]吲哚，来自各种2-叠氮基苯甲醛，仲胺和末端炔烃。此一锅串联反应的最佳反应条件很简单，可在室温下进行，并能以高收率（最高84％）生产相应的产物。发现2-叠氮苯甲醛和末端炔的分子间[3 + 2]环加成反应是目前开发的以2-三唑苯甲醛为次要产物的串联反应的竞争反应。后者也被分离和表征。