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Thermal, photo-oxidation and antimicrobial studies of linalyl acetate as a major ingredient of lavender essential oil
Arabian Journal of Chemistry ( IF 6 ) Pub Date : 2020-01-01 , DOI: 10.1016/j.arabjc.2017.12.008
Suzan Khayyat

Abstract Lavender oil, obtained from the flowers of Lavandula angustifolia (Family: Lamiaceae) by steam distillation, The major component of lavender oil is linalyl acetate was isolated and subjected to oxidation thermally and photochemically using (mcpba and H2O2) respectively to produce mixture of 6,7-epoxy-3,7-dimethyl-1-octene-3-yl acetate (3) and 1,2-epoxy-3,7-dimethyl-6-octene-3-yl acetate (4) photochemically, while produced epoxide 4 only thermally. On the other hand, photooxygenation of 1 using different singlet oxygen sensitizers gave two hydroperoxide derivatives of 6-hydroperoxy-3,7-dimethylocta-1,7-diene-3-yl acetate (5) and 7-hydroperoxy-3,7-dimethylocta-1,5-diene-3-yl acetate (6) in the presence of tetraphenyl porphin (TPP), whereas gave hydroperoxide 6 only using hematoporphyrin (HP). Studies on the antimicrobial especially Microsporum canis and Microsprum gallinna showed that linalyl acetate and its epoxide and hydroperoxide derivatives have a good antibacterial action.

中文翻译:

作为薰衣草精油主要成分的乙酸芳樟酯的热、光氧化和抗菌研究

摘要 薰衣草油是从狭叶薰衣草(科:唇形科)的花中通过水蒸气蒸馏获得的,薰衣草油的主要成分是乙酸芳樟酯,分别使用(mcpba 和 H2O2)进行热氧化和光化学氧化,得到 6 ,7-环氧-3,7-二甲基-1-辛烯-3-基乙酸酯 (3) 和 1,2-环氧-3,7-二甲基-6-辛烯-3-基乙酸酯 (4),同时产生环氧化物 4 仅热作用。另一方面,使用不同的单线态氧敏化剂对 1 进行光氧化得到 6-氢过氧-3,7-二甲基辛基-1,7-二烯-3-基乙酸酯 (5) 和 7-氢过氧-3,7-的两种氢过氧化物衍生物在四苯基卟啉 (TPP) 存在下生成二甲基辛基-1,5-二烯-3-基乙酸酯 (6),而仅使用血卟啉 (HP) 生成氢过氧化物 6。
更新日期:2020-01-01
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