The eventual role played by Brønsted and Lewis acid sites on pyruvaldehyde Cannizzaro reaction to lactic acid was investigated in a flow reactor using different catalysts bearing different acidity. It was shown that Lewis acid sites on heterogeneous catalysts are crucial for the reaction while Brønsted sites play no role at all. The results revealed that catalytic activity is indeed directly related to catalyst acidity. TiO₂, ZrO₂ and Nb₂O₅ were the most promising catalysts and their activity was related to their water-tolerant Lewis acid sites. Nb₂O₅ was shown to be the most active and stable catalyst while ZnO underwent a fast deactivation process ascribed to the formation of amorphous carbonaceous materials as revealed by TG and laser Raman spectroscopy.

在使用不同酸度的不同催化剂的流动反应器中，研究了Brønsted和Lewis酸位在丙酮醛Cannizzaro与乳酸反应中的最终作用。结果表明，多相催化剂上的路易斯酸位对于反应至关重要，而布朗斯台德位根本不起作用。结果表明，催化活性确实与催化剂的酸度直接相关。TiO ₂，ZrO ₂和Nb ₂ O ₅是最有前途的催化剂，它们的活性与其耐水路易斯酸位有关。铌₂ O ₅ TG和激光拉曼光谱表明，ZnO是最活泼，最稳定的催化剂，而ZnO则经历了快速失活的过程，这归因于非晶碳质材料的形成。