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Effect of the consumption of a synbiotic diet mousse containing Lactobacillus acidophilus La-5 by individuals with metabolic syndrome: A randomized controlled trial
Journal of Functional Foods ( IF 3.8 ) Pub Date : 2017-12-22 , DOI: 10.1016/j.jff.2017.12.041
Douglas Xavier-Santos , Egidio Dorea Lima , Andréa Name Colado Simão , Raquel Bedani , Susana Marta Isay Saad

This study aimed to evaluate the impact of a synbiotic diet mousse containing Lactobacillus acidophilus La-5 and the prebiotics inulin and fructooligosaccharides on anthropometric and blood pressure measurements, biochemical, inflammatory, haematological, and immunological parameters of volunteers with metabolic syndrome (MetS). In a randomized, double-blind, placebo-controlled trial, forty-five volunteers with MetS were assigned into two groups, each receiving 40 g/day of: synbiotic diet mousse (SDM) (n = 23) and placebo diet mousse (PDM) without pro- and prebiotics (n = 22). All the evaluated parameters were measured at the beginning and after 8 weeks of intervention. The daily intake of SDM and PDM led to significant reductions of total cholesterol and HDL-cholesterol, as well as of immunoglobulins (A and M), and interleukin-1β in both groups (p < .05). These results suggest that the presence of the probiotic and prebiotic ingredients in the diet mousse did not show any additional effects on the parameters evaluated in volunteers with MetS.



中文翻译:

代谢综合征患者食用嗜酸乳杆菌La-5的合生素饮食慕斯的影响:一项随机对照试验

这项研究旨在评估含嗜酸乳杆菌的合生素饮食慕斯的影响La-5和益生元菊粉和低聚果糖对人体代谢综合征(MetS)的人体测量和血压测量,生化,炎症,血液学和免疫学参数的影响。在一项随机,双盲,安慰剂对照试验中,将四十五名患有MetS的志愿者分为两组,每组每天接受40克/天的剂量:合生素饮食摩丝(SDM)(n = 23)和安慰剂饮食摩丝(PDM) ),不含益生元和益生元(n = 22)。在干预开始和干预后8周测量所有评估的参数。每天摄入SDM和PDM导致两组的总胆固醇和HDL-胆固醇以及免疫球蛋白(A和M)以及白介素-1β显着降低(p <.05)。这些结果表明,饮食慕斯中益生菌和益生元成分的存在对MetS志愿者评估的参数没有显示任何其他影响。

更新日期:2017-12-22
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