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On the Race to Starvation: How Do Bacteria Survive High Doses of Antibiotics?
Molecular Cell ( IF 16.0 ) Pub Date : 2017-12-21 , DOI: 10.1016/j.molcel.2017.12.004
Yusuf Talha Tamer , Erdal Toprak

In this issue of Molecular Cell, Gutierrez et al. (2017) unravel a bacterial survival strategy that they term “density-dependent persistence” or DDP. The authors demonstrate that the majority of isogenic cells in bacterial populations survive lethal antibiotic doses once bacteria consume nutrients and enter stationary growth phase.



中文翻译:

在挨饿的竞赛中:细菌如何生存高剂量的抗生素?

在本期《分子细胞》中,古铁雷斯(Gutierrez)等人。(2017)提出了一种细菌生存策略,他们称之为“密度依赖性持久性”或DDP。作者证明,一旦细菌消耗了养分并进入稳定的生长期,细菌种群中的大多数同基因细胞就可以承受致命的抗生素剂量。

更新日期:2017-12-21
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