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Coplanarity driven fluorescence turn-on sensor for chromium(iii) and its application for bio-imaging†
Photochemical & Photobiological Sciences ( IF 2.7 ) Pub Date : 2017-12-22 00:00:00 , DOI: 10.1039/c7pp00425g
G. Balamurugan 1, 2, 3, 4, 5 , S. Velmathi 1, 2, 3, 4, 5
Affiliation  

New benzimidazole and benzothiazole derivatives (S1–S3) derived from thiophene-2,5-dicarboxaldehyde and 5,5′-bipyridyldicarboxaldehyde with NSN/SSS/NN binding sites were tested against various cations and anions. S3 showed selectivity toward copper(II) ions among other cations under consideration with the colour change to pale yellow from colourless under aqueous medium. In the cases of S1 and S2, no colour change was observed. S1 alone showed selective fluorescence turn on for Cr(III) ions among other cations. S1 showed sensitivity towards Cr(III) with fluorescence change with bathochromic shift. The prominent fluorescence change of S1 with Cr(III) ions was applied to live cell imaging of HeLa cells.

中文翻译:

铬(iii)的共面驱动荧光开启传感器及其在生物成像中的应用

测试了具有NSN / SSS / NN结合位点的噻吩-2,5-二甲苯甲醛和5,5'-联吡啶二苯甲醛的新苯并咪唑和苯并噻唑衍生物(S1-S3)对抗各种阳离子和阴离子的影响。考虑到在其他阳离子中,S3对铜(II)离子表现出选择性,并且在水性介质中颜色从无色变为浅黄色。在S1S2的情况下,未观察到颜色变化。单独的S1对其他阳离子中的Cr(III)离子显示选择性的荧光开启。S1对Cr(III)随着红移而荧光变化。S1与Cr(III)离子的显着荧光变化被应用于HeLa细胞的活细胞成像。
更新日期:2017-12-22
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