The influence of chemical degradation during dietary exposures to fish on biomagnification factors and bioaccumulation factors†,Environmental Science: Processes & Impacts

当前位置： X-MOL 学术 › Environ. Sci.: Processes Impacts › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

The influence of chemical degradation during dietary exposures to fish on biomagnification factors and bioaccumulation factors†
Environmental Science: Processes & Impacts ( IF 4.3 ) Pub Date : 2017-12-22 00:00:00 , DOI: 10.1039/c7em00539c
Jon A. Arnot _{1,

2,

3,

4,

5} , Donald Mackay _{3,

6,

7,

8,

9}

Affiliation

The chemical dietary absorption efficiency (E_D) quantifies the amount of chemical absorbed by an organism relative to the amount of chemical an organism is exposed to following ingestion. In particular, E_D can influence the extent of bioaccumulation and biomagnification for hydrophobic chemicals. A new E_D model is developed to quantify chemical process rates in the gastrointestinal tract (GIT). The new model is calibrated with critically evaluated measured E_D values (n = 250) for 80 hydrophobic persistent chemicals. The new E_D model is subsequently used to estimate chemical reaction rate constants (k_R) assumed to occur in the lumen of the GIT from experimental dietary exposure tests (n = 255) for 165 chemicals. The new k_R estimates are corroborated with k_R estimates for the same chemicals from the same data derived previously by other methods. The roles of k_R and the biotransformation rate constant (k_B) on biomagnification factors (BMFs) determined under laboratory test conditions and on BMFs and bioaccumulation factors (BAFs) in the environment are examined with the new model. In this regard, differences in lab and field BMFs are highlighted. Recommendations to address uncertainty in E_D and k_R data are provided.

中文翻译：

饮食中鱼的化学降解对生物放大系数和生物蓄积系数的影响†

化学食物的吸收效率（E _D）量化了生物体相对于生物体在摄入后所接触的化学物质的量所吸收的化学物质的量。特别地，E _D可以影响疏水性化学品的生物积累和生物放大程度。开发了一种新的E _D模型来量化胃肠道（GIT）中的化学过程速率。新模型通过对80种疏水性持久性化学品的严格评估的E _D值（n = 250）进行了校准。新的E _D模型随后用于估算化学反应速率常数（k_R）假定是针对165种化学物质的实验性饮食暴露测试（ n = 255）发生在GIT腔中。新ķ _ř估计证实与ķ _ř概算通过其它方法预先获得的相同的数据的相同的化学物质。的作用ķ _ř和生物转化速率常数（ ķ_乙对实验室试验条件下和对生物放大系数并在环境生物累积因子（BAFs）确定生物放大因子（BMFs））进行检查与新模型。在这方面，突出了实验室和现场BMF的差异。解决E _D和E中不确定性的建议提供了k _R个数据。

更新日期：2017-12-22

点击分享查看原文

点击收藏

阅读更多本刊最新论文