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Sugar fuels T-cell memory
Nature Cell Biology ( IF 17.3 ) Pub Date : 2017-12-21 , DOI: 10.1038/s41556-017-0014-y Joanna Olivas , Tiffany Horng
Nature Cell Biology ( IF 17.3 ) Pub Date : 2017-12-21 , DOI: 10.1038/s41556-017-0014-y Joanna Olivas , Tiffany Horng
Sugar fuels T-cell memory
中文翻译:
糖促进T细胞记忆
糖促进T细胞记忆
更新日期:2017-12-21
Sugar fuels T-cell memory, Published online: 21 December 2017; doi:10.1038/s41556-017-0014-y
Previous work has highlighted the role of metabolic shifts in regulating the formation of memory T cells, which are generated during a primary infection to provide long-lasting immunity. A study now shows that memory T cells rely on a gluconeogenesis–glycogenolysis cycle to provide antioxidant defence and support their survival.中文翻译:
糖促进T细胞记忆
糖促进T细胞记忆
糖助长T细胞记忆,在线发布:2017年12月21日; doi:10.1038 / s41556-017-0014-y
先前的工作强调了代谢转移在调节记忆T细胞形成中的作用,该记忆T细胞是在原发感染过程中产生的,以提供持久的免疫力。现在的一项研究表明,记忆T细胞依靠糖异生-糖原分解循环来提供抗氧化防御并支持其生存。