Palladium-catalyzed enantioselective C(sp²)–H activation of ferrocenyl ketones is achieved through utilizing catalytic, inexpensive L-tert-leucine as a chiral transient directing group. The transformation allows rapid access to ferrocene scaffolds simultaneously possessing planar- and stereogenic central chirality, widely applied in the ferrocene-based chiral ligand families.

中文翻译：

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钯催化的二茂铁基酮的对映体选择性C（sp ²）–H芳基化由手性瞬态导向基团实现

钯-催化的对映选择性C（SP ²）-H的二茂铁酮的活化是通过利用催化的，廉价的实现大号-叔-亮氨酸作为手性瞬态引导组。该转化允许快速获得同时具有平面和立体中心手性的二茂铁支架，广泛应用于基于二茂铁的手性配体家族。