We report a novel synthetic and processing methodology for the preparation of doubly dynamic, self-healing, 3D-printable macroporous gels. 3D-printable oxime hydrogels were prepared by cross-linking poly(n-hydroxyethyl acrylamide-co-methyl vinyl ketone) (PHEAA-co-PMVK) with a bifunctional hydroxylamine. 3D-printed oxime hydrogels were subjected to post-printing treatment by thermally induced phase separation (TIPS), which facilitated the formation of hydrogen bonding and oxime cross-links, and dramatically increased the mechanical strength of soft oxime objects in a well-controlled manner by up to ∼1900%. The mechanical properties of the cryogels were tuned by freezing conditions, which affected the microstructure of the cryogels. These doubly dynamic 3D-printed cryogels are macroporous, exhibit outstanding swelling performances, and can fully, rapidly and autonomously self-heal.

中文翻译：

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具有可调节特性的动态自修复冰晶3D打印†

我们报告了一种新型的合成和加工方法，用于制备双动态，自修复，3D可打印的大孔凝胶。通过交联聚（n-羟乙基丙烯酰胺-共-甲基乙烯基酮）（PHEAA-共）制备3D可印刷的肟水凝胶-PMVK）与双功能羟胺。通过热诱导相分离（TIPS）对3D打印的肟水凝胶进行印后处理，这有助于形成氢键和肟交联，并以可控的方式显着提高了软肟对象的机械强度高达〜1900％。通过冻结条件来调整冰晶格的机械性能，这会影响冰晶格的微观结构。这些双重动态3D打印的冰晶是大孔的，具有出色的溶胀性能，并且可以完全，快速和自主地自我修复。