One of the most enduring truisms in transplantation of all organs was written by Starzl almost 60 years ago: “The provision of a viable and minimally damaged homograft is undoubtedly the most important single factor in the determinant of success.”¹ Presently, there are far more patients in need of transplant than there are organs available, and the use of expanded criteria donors has become an important source of organs for an ever-increasing acuity of patients. Consequently, the specter of graft failure and the ability to assess and predict outcomes to better intervene with management strategies has become the frontier in transplantation.

中文翻译：

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肝移植失败的决定因素

Starzl在大约60年前就写下了所有器官移植中最持久的事实：“毫无疑问，提供可行且损伤最小的同种异体移植物是决定成功的最重要的单一因素。” ¹目前，需要移植的患者数量远远超过可用器官，并且使用扩展标准的供体已成为患者视力不断提高的重要器官来源。因此，移植失败的幽灵以及评估和预测结果以更好地干预治疗策略的能力已成为移植的前沿领域。