This week’s articles showed that enhancing a mitochondrial stress response reduced amyloid aggregation in mice; solved the structure of the ion channel TRPM4; found a role for NOTCH1 in the assembly of adherens junctions and endothelial barrier maintenance; and showed that RNA polymerase III limits life span in worms and flies.

中文翻译：

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自然552（7684）中的笔记论文

本周的文章显示，增强线粒体应激反应可减少小鼠的淀粉样蛋白聚集。解决了离子通道TRPM4的结构；发现NOTCH1在粘附连接的组装和内皮屏障的维持中发挥了作用；并显示RNA聚合酶III限制了蠕虫和果蝇的寿命。