The findings of Jason H Y Wu and colleagues' pooled analysis¹ of linoleic acid and arachidonic acid biomarkers and incident type 2 diabetes should be interpreted with caution. Linoleic acid and arachidonic acid in serum are derived from the diet, but levels are controlled by the rate of peroxidation to bioactive metabolites. Serum linoleic acid or arachidonic acid status can be strongly affected by alcohol intake or smoking, which promote the formation of such metabolites.² The inflammatory potential of the overall diet can also affect fatty acid biomarkers.

中文翻译：

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亚油酸与糖尿病的预防

Jason HY Wu及其同事对亚油酸和花生四烯酸生物标志物以及2型糖尿病的合并分析¹的发现应谨慎解释。血清中的亚油酸和花生四烯酸均来自饮食，但其水平受过氧化成生物活性代谢物的速率的控制。饮酒或吸烟会严重影响血清亚油酸或花生四烯酸的状况，这会促进此类代谢产物的形成。²整体饮食的炎症潜能也可以影响脂肪酸的生物标志物。