Song Mao and Liangxia Wu correctly point out that establishing iodine status at the individual level remains challenging. Urinary iodine concentration is a reliable biomarker of iodine status at the population level, but not at the individual level.^1,2 Thus, whether all the pregnant women included in our study³ were iodine deficient remains unclear and exposure misclassification might have biased our results.

中文翻译：

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孕妇补充碘和儿童神经发育–作者的回复

宋茂和吴良霞正确地指出，在个人层面建立碘地位仍然具有挑战性。尿碘浓度是人群水平而不是个人水平的可靠碘状态生物标志物。^1,2因此，尚不清楚我们的研究³中包括的所有孕妇是否都缺碘，暴露分类错误可能使我们的结果产生偏差。