Mutant RAS is a major oncoprotein in human cancer and PD-L1 is a key driver of cancer immune evasion. In this issue of Immunity, Coelho et al. (2017) demonstrate that oncogenic RAS signaling promotes tumor immune escape by stabilizing PD-L1 mRNA.

中文翻译：

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RAS和PD-L1：癌症免疫逃逸的大师联络

突变的RAS是人类癌症中的主要癌蛋白，而PD-L1是逃避癌症的关键驱动力。在本期《免疫》中，Coelho等人。（2017）证明致癌RAS信号通过稳定PD-L1 mRNA促进肿瘤免疫逃逸。