The wound healing has remained a worldwide challenge as one of significant public health problems. Pathological scars and chronic wounds caused by injury, aging or diabetes lead to impaired tissue repair and regeneration. Due to the unique biological wound environment, the wound healing is a highly complicated process, efficient and targeted treatments are still lacking. Hence, research-driven to discover more efficient therapeutics is a highly urgent demand. Recently, the research results have revealed that microRNA (miRNA) is a promising tool in therapeutic and diagnostic fields because miRNA is an essential regulator in cellular physiology and pathology. Therefore, new technologies for wound healing based on miRNA have been developed and miRNA delivery has become a significant research topic in the field of gene delivery.

作为重要的公共卫生问题之一，伤口愈合一直是世界范围内的挑战。由伤害，衰老或糖尿病引起的病理性疤痕和慢性伤口会导致组织修复和再生受损。由于独特的生物伤口环境，伤口愈合是一个非常复杂的过程，仍然缺乏有效且有针对性的治疗方法。因此，迫切需要研究驱动以发现更有效的疗法。最近，研究结果表明，由于miRNA是细胞生理学和病理学中必不可少的调节剂，因此microRNA（miRNA）在治疗和诊断领域是一种有前途的工具。因此，已经开发了基于miRNA的伤口愈合新技术，并且miRNA递送已经成为基因递送领域中的重要研究课题。