The Front Cover shows photo‐triggered drug release from DNA‐microcapsules. The microcapsules were formed by assembly of the Y‐shaped DNA‐building blocks through hybridization of the corresponding overhang regions. Photoresponsive azobenzenes located within the connecting regions gave these DNA microcapsules photosensing abilities. Upon irradiation with light, the azobenzene units positioned at connecting regions between the building blocks were cis isomerized, and subsequently the microcapsules collapsed rapidly. This the resulted in the release of the doped compounds from the photosensing DNA microcapsule. More information can be found in the Full Paper by Yukiko Kamiya, Hiroyuki Asanuma et al. on page 2016 in Issue 24, 2017.

中文翻译：

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封面：用于光触发药物释放系统的DNA微胶囊（ChemMedChem 24/2017）

封面显示了光触发的DNA微胶囊中的药物释放。微胶囊是由Y形DNA构建块通过相应悬突区域的杂交组装而成的。位于连接区域内的光敏偶氮苯赋予了这些DNA微囊光敏能力。在光照射下，位于结构单元之间的连接区域的偶氮苯单元被顺式异构化，随后微胶囊迅速塌陷。这导致从光敏DNA微胶囊中释放出掺杂的化合物。有关更多信息，请参见神谷由纪子，浅沼弘之等人的论文全文。于2017年第24期，第2016页。