The GlycoDomainViewer is a bioinformatic tool to aid in the mining of glycoproteomic data sets from different sources and facilitate incorporation of glycosylation into studies of protein structure and function. We present a version 2.0 of GlycoDomainViewer incorporating a number of advanced features, which enhances visibility and accessibility of the wealth of glycoproteomic data being generated. The GlycoDomainViewer enables visual exploration of glycoproteomic data, incorporating information from recent N- and O-glycoproteome studies on human and animal cell lines and some organs and body fluids. The initial data comprises sites of glycosylation for N-linked, O-GalNAc, O-Fucose, O-Xyl, O-Mannose (in both human and yeast) and cytosolic O-GlcNAc type. The data made available via this tool will be regularly updated to improve the coverage of known glycosylation sites and data sets, reflecting the advances currently being made in characterisation of glycoproteomes. The tool is available at https://glycodomain.glycomics.ku.dk.

中文翻译：

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GlycoDomainViewer：一种用于糖蛋白组背景研究的生物信息学工具

GlycoDomainViewer是一种生物信息学工具，可帮助挖掘来自不同来源的糖蛋白组学数据集，并有助于将糖基化纳入蛋白质结构和功能研究中。我们提出了GlycoDomainViewer的2.0版，其中集成了许多高级功能，从而增强了所生成的大量糖蛋白组学数据的可见性和可访问性。GlycoDomainViewer可以对糖蛋白质组学数据进行可视化探索，并结合了有关人和动物细胞系以及某些器官和体液的最新N和O糖蛋白质组学研究的信息。初始数据包括N-连接的，O-GalNAc，O-岩藻糖，O-Xyl，O-甘露糖（在人和酵母中）和胞质O-GlcNAc类型的糖基化位点。通过该工具提供的数据将定期更新，以改善已知糖基化位点和数据集的覆盖范围，反映出糖蛋白组学表征方面的最新进展。该工具位于https://glycodomain.glycomics.ku.dk。