AbstractThe effect of graphene nanosheets on the glucose sensing performance of CuO powders was investigated. CuO and graphene-modified CuO nanoparticles (NPs) were fabricated by microwave-assisted synthesis and characterized by X-ray diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy. The material was placed on a glassy carbon electrode (GCE) which then was characterized by cyclic voltammetry and chronoamperometry with respect to the capability of sensing glucose both at pH 13 and pH 7.4. The results revealed that the modified GCE has a fast and selective linear response to glucose at pH 13 that covers the 0.21 μM to 12 mM concentration range, with a 0.21 μM low detection limit. The presence of graphene nanosheets results in an improved sensitivity which is to 700 μA mM−1 cm−2. In solution of pH 7.4, the respective data are a linear analytical range from 5 to 14 mM; a 5 μM LOD and a sensitivity of 37.63 μA mM−1 cm−2 at working potential of −0.05 V (vs. Ag/AgCl) and scan rate of 50 mV s−1. Ascorbic acid, dopamine, uric acid, sucrose, maltose and fructose do not interfere. Graphical abstractᅟ

中文翻译：

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微波辅助合成石墨烯修饰的氧化铜纳米粒子，用于在生物 pH 值下对葡萄糖进行无酶伏安法检测

摘要 研究了石墨烯纳米片对CuO粉体葡萄糖传感性能的影响。CuO 和石墨烯修饰的 CuO 纳米粒子 (NPs) 通过微波辅助合成制备，并通过 X 射线衍射、透射电子显微镜和 X 射线光电子能谱表征。将该材料置于玻璃碳电极 (GCE) 上，然后通过循环伏安法和计时电流法表征其在 pH 13 和 pH 7.4 下检测葡萄糖的能力。结果表明，改良的 GCE 在 pH 13 下对葡萄糖具有快速且选择性的线性响应，涵盖 0.21 μM 至 12 mM 的浓度范围，检测下限为 0.21 μM。石墨烯纳米片的存在导致灵敏度提高到 700 μA mM-1 cm-2。在 pH 7.4 的溶液中，各自的数据是从 5 到 14 mM 的线性分析范围；5 μM LOD 和 37.63 μA mM-1 cm-2 的灵敏度，在 -0.05 V（相对于 Ag/AgCl）的工作电位和 50 mV s-1 的扫描速率下。抗坏血酸、多巴胺、尿酸、蔗糖、麦芽糖和果糖不会产生干扰。图形摘要ᅟ