18 www.thelancet.com/neurology Vol 17 January 2018 tools for sleep disorders into clinical practice. Despite this recognition of a close link between sleep and cardiometabolic health, there is a paucity of data on sleep quality and risk of adverse pregnancy outcomes. Recent research indicates that obstructive sleep apnoea is a risk factor associated with cardiometabolic disease, but the role of sleep and circadian rhythms have been less appreciated. In 2017, a few publications examining sleep and health during pregnancy have emerged. One such study was the first to use an objective estimate of sleep (as measured by wrist actigraphy) in a large cohort of pregnant women (n=782) to ascertain whether sleep was associated with risk of gestational diabetes, a condition that can cause adverse health outcomes for mother and baby. The authors found that both shorter sleep duration and a later midpoint of sleep, independent of sleep duration, were associated with an increased risk of gestational diabetes. These findings suggest that assessment of sleep duration and sleep timing is important for maternal-fetal health and that improving sleep duration and sleeping at an earlier clock time might be beneficial for pregnant women. Research in 2017 highlighted the importance of sleep quality (both duration and timing) and appropriately synchronised circadian rhythms on neurological and cardiometabolic health. Future research aiming to develop sleep and circadian-based therapies has the potential to improve neurological health outcomes.

中文翻译：

---

2017年神经系统感染研究进展

18 www.thelancet.com/neurology Vol 2018 年 1 月 17 日将睡眠障碍纳入临床实践的工具。尽管人们认识到睡眠与心脏代谢健康之间存在密切联系，但关于睡眠质量和不良妊娠结局风险的数据却很少。最近的研究表明，阻塞性睡眠呼吸暂停是与心脏代谢疾病相关的危险因素，但睡眠和昼夜节律的作用却鲜为人知。2017 年，出现了一些研究孕期睡眠和健康的出版物。一项此类研究首次在一大群孕妇 (n=782) 中使用客观的睡眠评估（通过腕部活动描记法测量）来确定睡眠是否与妊娠糖尿病风险相关，妊娠糖尿病是一种可能导致不良反应的疾病。母亲和婴儿的健康结果。作者发现，较短的睡眠时间和较晚的睡眠中点，与睡眠时间无关，都与妊娠糖尿病风险增加有关。这些研究结果表明，睡眠持续时间和睡眠时间的评估对母胎健康很重要，改善睡眠持续时间和在更早的时钟时间睡觉可能对孕妇有益。2017 年的研究强调了睡眠质量（持续时间和时间）和适当同步的昼夜节律对神经和心脏代谢健康的重要性。旨在开发基于睡眠和昼夜节律的疗法的未来研究有可能改善神经系统健康结果。与妊娠糖尿病风险增加有关。这些研究结果表明，睡眠持续时间和睡眠时间的评估对母胎健康很重要，改善睡眠持续时间和在更早的时钟时间睡觉可能对孕妇有益。2017 年的研究强调了睡眠质量（持续时间和时间）和适当同步的昼夜节律对神经和心脏代谢健康的重要性。旨在开发基于睡眠和昼夜节律的疗法的未来研究有可能改善神经系统健康结果。与妊娠糖尿病风险增加有关。这些研究结果表明，睡眠持续时间和睡眠时间的评估对母胎健康很重要，改善睡眠持续时间和在更早的时钟时间睡觉可能对孕妇有益。2017 年的研究强调了睡眠质量（持续时间和时间）和适当同步的昼夜节律对神经和心脏代谢健康的重要性。旨在开发基于睡眠和昼夜节律的疗法的未来研究有可能改善神经系统健康结果。2017 年的研究强调了睡眠质量（持续时间和时间）和适当同步的昼夜节律对神经和心脏代谢健康的重要性。旨在开发基于睡眠和昼夜节律的疗法的未来研究有可能改善神经系统健康结果。2017 年的研究强调了睡眠质量（持续时间和时间）和适当同步的昼夜节律对神经和心脏代谢健康的重要性。旨在开发基于睡眠和昼夜节律的疗法的未来研究有可能改善神经系统健康结果。