A shell biorefinery would involve fractionation of crustacean shells and incorporation of the components into value‐added products, particularly those that contain nitrogen. In a proof‐of‐concept study that validates this concept, the anticancer alkaloid proximicin A has been synthesized from the chitin‐derived platform chemical 3‐acetamido‐5‐acetylfuran (3A5AF). This study accentuates the leading role chitin is likely to play in the sustainable production of nitrogen‐containing fine chemicals that are not directly attainable from lignocellulose.

中文翻译：

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迈向壳牌生物精炼厂：几丁质抗癌生物碱Proximicin A的可持续合成

壳生物精炼厂将涉及甲壳动物壳的分馏，并将这些成分掺入增值产品中，特别是含氮产品。在验证该概念的概念验证研究中，抗癌生物碱proximicin A是从几丁质衍生的平台化学3-乙酰胺基5-乙酰基呋喃（3A5AF）合成的。这项研究强调了几丁质可能在可持续生产含氮精细化学品中起着领导作用，而木质纤维素无法直接获得这些含氮精细化学品。