Oxidative R¹–H/R²–H cross-coupling represents an ideal way for the construction of new chemical bonds. However, the bond formation with loss of H₂ is typically thermodynamically unfavorable and thus usually requires an external driving force, namely, an appropriate sacrificial oxidant. Recent advances have revealed that oxidative R¹–H/R²–H cross-coupling with hydrogen gas evolution can be achieved through electrochemical anodic oxidation and concomitant cathodic proton reduction. Electrochemistry provides new opportunities for the construction of carbon-carbon and carbon-heteroatom bonds in an environmentally friendly manner. This review article gives an overview of the recent developments in this emerging field.

R ¹ -H / R ² -H的氧化交叉偶联是构建新化学键的理想方法。然而，具有H ₂损失的键形成通常在热力学上是不利的，因此通常需要外部驱动力，即适当的牺牲氧化剂。最近的进展表明，氧化R ¹ –H / R ²通过电化学阳极氧化和伴随的阴极质子还原，可以实现-H与氢气逸出的交叉偶联。电化学为以环境友好的方式构建碳-碳和碳-杂原子键提供了新的机会。这篇综述文章概述了这个新兴领域的最新发展。