Synthesis ( IF 2.2 ) Pub Date : 2017-12-14 , DOI: 10.1055/s-0036-1589520 Egor Verbitskiy 1, 2 , Gennady Rusinov 1, 2 , Oleg Chupakhin 1, 2 , Valery Charushin 1, 2
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Abstract
Data spanning the period 2000–2017 on the direct C–H functionalization of pyrimidines are collected and discussed in this review. This demonstrates the surge of interest and creativity that this field of chemistry has experienced during the last two decades. Plausible applications of highly functionalized pyrimidines are also discussed.
1 Introduction
2 Transition-Metal-Catalyzed C–H Functionalization of Pyrimidine Derivatives
3 Transition-Metal-Free Direct C–H Functionalization of Pyrimidine Derivatives
4 Deprotonative Metalation of Pyrimidine Derivatives
5 Conclusions
Data spanning the period 2000–2017 on the direct C–H functionalization of pyrimidines are collected and discussed in this review. This demonstrates the surge of interest and creativity that this field of chemistry has experienced during the last two decades. Plausible applications of highly functionalized pyrimidines are also discussed.
1 Introduction
2 Transition-Metal-Catalyzed C–H Functionalization of Pyrimidine Derivatives
3 Transition-Metal-Free Direct C–H Functionalization of Pyrimidine Derivatives
4 Deprotonative Metalation of Pyrimidine Derivatives
5 Conclusions
中文翻译：
嘧啶直接C–H功能化的最新进展
摘要
本文收集并讨论了2000年至2017年期间有关嘧啶直接C–H功能化的数据。这表明了化学领域在过去的二十年中经历的兴趣和创造力激增。还讨论了高度官能化的嘧啶的合理应用。
1引言
2嘧啶衍生物的过渡金属催化C–H功能化
3嘧啶衍生物的无过渡金属的直接C–H功能化
4嘧啶衍生物的去质子金属化
5。结论
本文收集并讨论了2000年至2017年期间有关嘧啶直接C–H功能化的数据。这表明了化学领域在过去的二十年中经历的兴趣和创造力激增。还讨论了高度官能化的嘧啶的合理应用。
1引言
2嘧啶衍生物的过渡金属催化C–H功能化
3嘧啶衍生物的无过渡金属的直接C–H功能化
4嘧啶衍生物的去质子金属化
5。结论
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