Reply to the ‘Comment on “Trimorphs of a pharmaceutical cocrystal involving two active pharmaceutical ingredients: potential relevance to combination drugs” by S. Aitipamula, P. S. Chow and R. B. H. Tan, CrystEngComm, 2009, 11, 1823’†,CrystEngComm

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Reply to the ‘Comment on “Trimorphs of a pharmaceutical cocrystal involving two active pharmaceutical ingredients: potential relevance to combination drugs” by S. Aitipamula, P. S. Chow and R. B. H. Tan, CrystEngComm, 2009, 11, 1823’†
CrystEngComm ( IF 3.1 ) Pub Date : 2017-12-13 00:00:00 , DOI: 10.1039/c7ce01979c
Srinivasulu Aitipamula _{1,

2,

3,

4,

5} , Pui Shan Chow _{1,

2,

3,

4,

5} , Reginald B. H. Tan _{1,

2,

3,

4,

5}

Affiliation

The inadvertent errors in the lattice energy calculations of the polymorphs reported in our previous article (CrystEngComm, 2009, 11, 1823–1827) were rectified. Form I (Refcode: QULLUF) was found to be the most thermodynamically stable polymorph by slurry experiments even though it has marginally higher lattice energy than the other two polymorphs.

中文翻译：

答复“ S. Aitipamula，PS Chow和RBH Tan撰写的关于“涉及两种活性药物成分的药物共晶体的三形体：与联合药物的潜在相关性”的评论，CrystEngComm，2009年，11月，1823年” †

在多晶型的晶格能计算的疏忽造成的错误在我们以前的文章（报道CrystEngComm，2009年，11，1823-1827）进行了纠正。通过浆液实验发现晶型I（Refcode：QULLUF）是热力学最稳定的多晶型物，尽管它的晶格能量比其他两种多晶型物略高。

更新日期：2017-12-13

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