Hippo signaling has a pivotal role in organ size control, tissue regeneration, and cancer. Recent studies have demonstrated critical functions of Hippo signaling in cancer immunity, innate immune responses against pathogens, and autoimmune diseases, refreshing our understanding of the implications of this pathway in the context of disease and therapy design.

中文翻译：

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免疫系统中的河马信号

河马信号在器官大小控制，组织再生和癌症中具有关键作用。最近的研究表明，河马信号传导在癌症免疫，针对病原体的先天免疫应答和自身免疫性疾病中具有关键作用，使我们对这种途径在疾病和治疗设计中的意义有了新的认识。