Communication is the sole means by which effective networking and co-existence is accomplished amongst living beings. Microbes have their own chit-chats. Science has overheard these microbial gossips and have concluded that these aren't just informal communications, but carefully coordinated signals that plan their effective strategies. Tracking one such signal molecule, N-acyl homoserine lactone (AHL), led to a fundamental understanding to microbial quorum sensing (QS). Furtherance of research sought for ways to cut off communication between these virulent forms, so as to hinder their combinatorial attacks through quorum sensing inhibitors (QSIs). A clear understanding of the inhibitors of these microbial communication systems is vital to destroy their networking and co-working. The current review, consolidates the solutions for QSIs offered from natural sources against these micro components, that are capable of slaughtering even nature's most fit entity-man. The applications of effective out sourcing of this QSI technologies and the need for development are discussed. The importance of silencing this microbial chatter to various aspects of human life and their implications are discussed and elaborated.

沟通是在众生之间实现有效的网络和共存的唯一手段。微生物有自己的闲聊。科学发现了这些微生物八卦，并得出结论，这些微生物不仅仅是非正式的交流，而是精心协调的信号，以规划其有效策略。追踪一个这样的信号分子N-酰基高丝氨酸内酯（AHL）导致对微生物群体感应（QS）的基本了解。进一步的研究寻求切断这些毒性形式之间的交流的方式，以阻止通过群体感应抑制剂（QSI）的组合攻击。明确了解这些微生物传播系统的抑制因素对于破坏它们的网络和协同工作至关重要。当前的审查整合了自然资源提供的针对这些微组件的QSI解决方案，这些微组件甚至可以屠杀自然界最合适的实体人。讨论了该QSI技术的有效外包应用和开发需求。讨论并阐述了使微生物chat声对人类生活各个方面及其影响的重要性。