Cardiovascular diseases and diabetes are the biggest causes of death globally. Therefore, prevention of these diseases is a focus of pharmaceuticals and functional food manufacturers. This review summarizes recent research trends and scientific knowledge in seaweed protein-derived peptides with particular emphasis on production, isolation and potential health impacts in prevention of hypertension, diabetes and oxidative stress. The current status and future prospects of bioactive peptides are also discussed. Bioactive peptides have strong potential for use in therapeutic drug and functional food formulation in health management strategy, especially cardiovascular disease and diabetes. Seaweeds can be used as sustainable protein sources in the production of these peptide-based drugs and functional foods for preventing such diseases. Many studies have reported that peptides showing angiotensin converting enzyme inhibition, antihypertensive, antioxidative and antidiabetics activities, have been successfully isolated from seaweed. However, further research is needed in large-scale production of these peptides, efficient isolation methods, interactions with functional foods and other pharmaceuticals, and their ease to digestion in in vivo studies and safety to validate the health benefits of these peptides.

中文翻译：

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源自海藻蛋白的生物活性肽及其健康益处：抗高血压、抗氧化和抗糖尿病特性

心血管疾病和糖尿病是全球最大的死亡原因。因此，预防这些疾病是药品和功能性食品制造商的重点。本综述总结了海藻蛋白衍生肽的最新研究趋势和科学知识，特别强调了在预防高血压、糖尿病和氧化应激方面的生产、分离和潜在健康影响。还讨论了生物活性肽的现状和未来前景。生物活性肽在健康管理策略中的治疗药物和功能性食品配方中具有强大的潜力，尤其是心血管疾病和糖尿病。海藻可以作为可持续的蛋白质来源，用于生产这些基于肽的药物和预防此类疾病的功能性食品。许多研究报告称，已成功从海藻中分离出显示血管紧张素转化酶抑制、抗高血压、抗氧化和抗糖尿病活性的肽。然而，需要进一步研究这些肽的大规模生产、有效的分离方法、与功能性食品和其他药物的相互作用，以及它们在体内研究中的易消化性和安全性，以验证这些肽的健康益处。