The article introduces a novel method for accelerated analysis of membrane fouling during ultrafiltration of colloids: centrifugal ultrafiltration with a stepwise change of centrifugal rotation speed. The method allows simultaneous analysis of membrane fouling for different colloidal samples in a single analytical centrifugation experiment. The analysis for determination of fouled membrane resistance, specific cake resistance and reversibility of the filter cake compression is provided. The method applicability was tested with bovine serum albumin solutions at different protein concentrations. Fouled membrane resistance as well as pressure dependency of specific cake resistance was determined in a wide pressure range of 10…450 kPa. Results obtained with the help of the proposed method were in a good agreement with those obtained using the conventional method of constant pressure dead-end ultrafiltration.

本文介绍了一种在胶体超滤过程中加速膜结垢分析的新方法：离心式超滤，并逐步改变离心转速。该方法允许在单个分析离心实验中同时分析不同胶体样品的膜污染情况。提供确定污垢膜阻力，比滤饼阻力和滤饼压缩可逆性的分析。用不同蛋白浓度的牛血清白蛋白溶液测试了该方法的适用性。在10…450 kPa的宽压力范围内测定了膜的结垢阻力以及比饼阻力的压力依赖性。