In this review article, we will examine the history of polymers and their evolution from provisional World War II materials to medical therapeutics. To provide a comprehensive look at the current state of polymer-based therapeutics, we will classify technologies according to targeted areas of interest, including central nervous system-based and intraocular-, gastrointestinal-, cardiovascular-, dermal-, reproductive- , skeletal-, and neoplastic-based systems. Within each of these areas, we will consider several examples of novel, clinically available polymerbased therapeutics; in addition, this review will also include a discussion of developing therapies, ranging from the in vivo to clinical trial stage, for each targeted area of treatment. Finally, we will emphasize areas of patient care in need of more effective, accessible, and targeted treatment approaches where polymer-based therapeutics may offer potential solutions.

在这篇评论文章中，我们将研究聚合物的历史以及它们从第二次世界大战临时材料到医学治疗剂的演变。为了全面了解聚合物疗法的当前状态，我们将根据关注的目标领域对技术进行分类，包括基于中枢神经系统的以及眼内，胃肠道，心血管，皮肤，生殖，骨骼等方面的技术。以及基于肿瘤的系统。在这些领域中的每一个领域，我们将考虑一些新颖的，可临床使用的基于聚合物的治疗剂的例子。此外，本综述还将讨论针对每个靶向治疗领域的开发方法的讨论，从体内到临床试验阶段不等。最后，我们将强调需要更有效，更容易获得，