Antimicrobial cationic polymers mainly contain two functional components: the cationic groups and the hydrophobic groups. The antimicrobial activity is influenced by the type, amount, location and distribution of these two components. This review summarizes the designs and syntheses of antimicrobial cationic polymers by controlling the above two factors. It involves the structural designs from primary to secondary structures, from covalent to noncovalent syntheses and from bulk to surface. Furthermore, it will discuss how to advance structural designs toward functional controls for optimizing the antimicrobial performances and biocompatibility of antimicrobial cationic polymers. It is anticipated that this review will provide some guidelines for developing molecular engineering of antimicrobial cationic polymers with tailor-made structures and functions. Antimicrobial cationic polymers mainly contain two functional components: the cationic groups and the hydrophobic groups. The antimicrobial activity is influenced by the type, amount, location and distribution of these two components. This review summarizes the structural designs of antimicrobial cationic polymers from primary to secondary structures, from covalent to noncovalent syntheses and from bulk to surface. It will provide some guidelines for developing molecular engineering of antimicrobial cationic polymers with tailor-made structures and functions.

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抗菌阳离子聚合物：从结构设计到功能控制

抗菌阳离子聚合物主要包含两种功能成分：阳离子基团和疏水基团。抗菌活性受这两种成分的类型、数量、位置和分布影响。本综述通过控制上述两个因素总结了抗菌阳离子聚合物的设计和合成。它涉及从一级结构到二级结构、从共价合成到非共价合成以及从本体到表面的结构设计。此外，它将讨论如何推进结构设计以实现功能控制，以优化抗菌阳离子聚合物的抗菌性能和生物相容性。预计该综述将为开发具有定制结构和功能的抗菌阳离子聚合物的分子工程提供一些指导。抗菌阳离子聚合物主要包含两种功能成分：阳离子基团和疏水基团。抗菌活性受这两种成分的类型、数量、位置和分布影响。这篇综述总结了抗菌阳离子聚合物从一级结构到二级结构、从共价合成到非共价合成以及从本体到表面的结构设计。它将为开发具有定制结构和功能的抗菌阳离子聚合物的分子工程提供一些指导。阳离子基团和疏水基团。抗菌活性受这两种成分的类型、数量、位置和分布影响。这篇综述总结了抗菌阳离子聚合物从一级结构到二级结构、从共价合成到非共价合成以及从本体到表面的结构设计。它将为开发具有定制结构和功能的抗菌阳离子聚合物的分子工程提供一些指导。阳离子基团和疏水基团。抗菌活性受这两种成分的类型、数量、位置和分布影响。这篇综述总结了抗菌阳离子聚合物从一级结构到二级结构、从共价合成到非共价合成以及从本体到表面的结构设计。它将为开发具有定制结构和功能的抗菌阳离子聚合物的分子工程提供一些指导。