The Korean Cancer Prevention Study-II (KCPS-II) Biobank is a large blood-based cohort study with long-term follow-up via a unique linkage of routine, nationwide medical examinations conducted at health promotion centres across South Korea with records for mortality and hospitalization. It was initiated in April 2004 and has been supported by the Seoul city government since December 2005. In addition to the examination of cancer, a major reason for the cohort being established was to examine the determinants and long-term consequences of the metabolic syndrome—a term used to describe the co-occurrence of increased blood pressure, high blood sugar, excess central adiposity and elevated cholesterol or triglyceride levels—which has been shown in many studies to be associated with a substantially increased risk of cardiovascular diseases (CVD),^1–4 as well as some cancers.^5,6 However, through its large sample size, detailed mortality and morbidity linkage and, crucially, availability of baseline blood samples for all participants, the cohort is now well placed to assess the relevance to health of a much wider range of personal health behaviours and physical and biological characteristics (including genetics).

中文翻译：

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队列资料：韩国癌症预防研究II（KCPS-II）生物库

韩国癌症预防研究II（KCPS-II）生物库是一项大型的基于血液的队列研究，通过在韩国各地健康促进中心进行的常规全国性医学检查与死亡记录的独特关联，可以进行长期随访和住院。该计划始于2004年4月，自2005年12月以来一直得到首尔市政府的支持。除了进行癌症检查之外，建立该队列的一个主要原因是检查代谢综合征的决定因素和长期后果-该术语用于描述血压升高，高血糖，过多的中央肥胖和胆固醇或甘油三酯水平升高的共同发生，许多研究表明，该疾病与心血管疾病（CVD）的风险显着增加有关，^1-4以及某些癌症。^{5 ，6}然而，通过其大的样本大小，详细死亡率和发病率联动，并且重要的是，基线血液样品用于所有参与者的可用性，队列现在很好地相关性评估范围更广个人健康行为的健康以及生理和生物学特征（包括遗传学）。