Atovaquone-proguanil is considered causal prophylaxis (inhibition of liver-stage schizonts) for Plasmodium falciparum; however, its causal prophylactic efficacy for Plasmodium vivax is not known. Travelers returning to nonendemic areas provide a unique opportunity to study P. vivax prophylaxis.

中文翻译：

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Vivax疟疾的化学预防：Atovaquone-Proguanil与其他选择相比的作用

Atovaquone-Proguanil被认为是恶性疟原虫的因果预防措施（抑制肝阶段裂殖体）；然而，其对间日疟原虫的因果预防功效尚不清楚。返回非流行地区的旅行者为研究间日疟原虫的预防提供了独特的机会。