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The role of central and medial amygdala in normal and abnormal aggression: A review of classical approaches
Neuroscience & Biobehavioral Reviews ( IF 7.5 ) Pub Date : 2017-09-14 , DOI: 10.1016/j.neubiorev.2017.09.017
Jozsef Haller

The involvement of the amygdala in aggression is supported by overwhelming evidence. Frequently, however, the amygdala is studied as a whole, despite its complex internal organization. To reveal the role of various subdivisions, here we review the involvement of the central and medial amygdala in male rivalry aggression, maternal aggression, predatory aggression, and models of abnormal aggression where violent behavior is associated with increased or decreased arousal. We conclude that: (1) rivalry aggression is controlled by the medial amygdala; (2) predatory aggression is controlled by the central amygdala; (3) hypoarousal-associated violent aggression recruits both nuclei, (4) a specific upregulation of the medial amygdala was observed in hyperarousal-driven aggression. These patterns of amygdala activation were used to build four alternative models of the aggression circuitry, each being specific to particular forms of aggression. The separate study of the roles of amygdala subdivisions may not only improve our understanding of aggressive behavior, but also the differential control of aggression and violent behaviors of various types, including those associated with various psychopathologies.



中文翻译:

中央杏仁核和内侧杏仁核在正常和异常侵略中的作用:经典方法综述

杏仁核参与侵略得到了压倒性证据的支持。但是,尽管内部结构复杂,但杏仁核通常作为一个整体进行研究。为了揭示各种细分的作用,在这里我们回顾了中央杏仁核和内侧杏仁核在男性竞争性侵略,母体侵略性,掠夺性侵略性以及异常侵略模型中的参与,在暴力侵害行为与增加或减少的唤醒相关。我们得出以下结论:(1)对抗性攻击是由内侧杏仁核控制的;(2)掠夺性攻击是由中央杏仁核控制的;(3)与房底相关的暴力侵略者募集了两个核,(4)在超房颤引起的侵略中,观察到了内侧杏仁核的特定上调。杏仁核激活的这些模式被用来建立四种侵略电路的替代模型,每种模型都特定于特定形式的侵略。对杏仁核细分的作用进行的单独研究不仅可以增进我们对攻击行为的理解,而且可以改善对各种类型的攻击和暴力行为(包括与各种心理病理学相关的行为)的差异控制。

更新日期:2017-09-14
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