Objective

To summarize findings of previous studies on the prevalence of trauma and Posttraumatic Stress Disorder (PTSD) in Conduct Disorder (CD).

Method

We conducted a systematic review and meta-analysis following the PRISMA guidelines. EBSCOhost, PubMed, CDSR and ARIF databases were searched in October 2016, employing relevant keywords.

Results

19 studies met inclusion criteria. Meta-analysis resulted in a lifetime PTSD prevalence of 11% (95% CI: 7–17%) in children and adolescents with CD, 14% (95% CI: 12–15%) in adults with pre-existing CD and 32% (95% CI: 25–40%) in juvenile offenders with CD. Higher lifetime PTSD prevalence was observed in individuals with than without CD, and in females compared to males with CD.

Conclusions

Studies focusing on the association of trauma, PTSD and CD are still relatively rare. Possible comorbidity models are discussed considering psychological and biological risk factors in a comprehensive model. The high rate of PTSD in CD may be due to shared risk factors; furthermore, CD might increase the risk for comorbid PTSD due to CD inherent risk taking behavior. To study pathways of risk, especially longitudinal studies are necessary.

中文翻译：

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创伤，创伤后应激障碍和行为障碍的关联：系统评价和荟萃分析

客观的

总结以前关于创伤和创伤后应激障碍（PTSD）在行为障碍（CD）中的患病率的研究结果。

方法

我们按照PRISMA指南进行了系统的审查和荟萃分析。2016年10月，使用相关关键字搜索了EBSCOhost，PubMed，CDRR和ARIF数据库。

结果

19个研究符合纳入标准。荟萃分析显示，患有CD的儿童和青少年的终生PTSD患病率为11％（95％CI：7–17％），患有CD的成人和成人中14％（95％CI：12–15％）和32 ％（95％CI：25–40％）在患有CD的少年犯中。患有CD的个体与未患有CD的个体相比，其一生中PTSD的患病率更高。

结论

专注于创伤，PTSD和CD的关联的研究仍然相对较少。在综合模型中考虑了心理和生物危险因素，讨论了可能的合并症模型。CD中PTSD的发生率高可能是由于共同的风险因素所致；此外，由于CD固有的冒险行为，CD可能会增加合并PTSD的风险。为了研究风险的途径，特别是纵向研究是必要的。