One unique platform, different PTMs: In addition to acetyl groups, deacetylases can remove other acyl modifications on lysines, the roles and regulation of which are far less understood. A versatile peptide‐based fluorescent probe for single‐reagent, real‐time detection of deacetylase activity that can be readily adapted for probing broader lysine deacylation is described.

中文翻译：

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基于肽的脱乙酰基酶和降糖基化酶活性的荧光探针：建立实时检测赖氨酸脱酰作用的通用平台

一个独特的平台，不同的PTM：除乙酰基外，脱乙酰基酶还可以去除赖氨酸上的其他酰基修饰，其作用和调控尚不清楚。本文介绍了一种基于肽的多功能荧光探针，可用于单试剂，实时检测脱乙酰酶活性，可以很容易地用于检测更广泛的赖氨酸脱酰作用。