Phenols are organic compounds with high antioxidant activity. Occurring mainly in plants, where they act as pigments or even as part of defense mechanisms against insects and herbivores. Given the positive impact on on human health, their isolation and purification from agricultural products is of particular interest for the production of nutritional, pharmaceutical and cosmetics supplements. In our study different materials rich in phenolic compounds were used, in order to separate the phenolic content and maximum condensation using physicochemical methods such as solvent extraction, filtration through membranes, adsorption/desorption on resins and vacuum distillation. The materials tested were solid wastes from winery, cocoa residuals, olive leaves, etc. The first step for the treatment was the extraction of phenolic content using water-ethanol solutions which was initially optimized. Then, sequential membrane filtration of the extracts by Ultrafiltration membranes, Nanofiltration and Reverse Osmosis was performed to separate the contained compounds, based on their molecular weight. To remove non-polar compounds, with similar molecular weights with phenols, methods of adsorption/desorption on specific resins were developed, in order final ethanolic solutions rich in phenolic compounds to be obtained. Finally, the ethanol was removed by vacuum evaporation at low temperatures. The purification of olive leaf phenols is illustrated in details in the present work. The final obtained concentrate, was a rich phenolic concentrate and contained 98 g/L phenols in gallic acid equivalents. This technique, after modification, can be applied to a variety of phenol-rich byproducts, allowing the operation of phenol separation plant adjustable to local agricultural activities.

苯酚是具有高抗氧化活性的有机化合物。主要发生在植物中，在植物中它们充当色素或什至是抵抗昆虫和草食动物的防御机制的一部分。鉴于其对人类健康的积极影响，将它们从农产品中分离和纯化对于生产营养，药物和化妆品补充剂尤为重要。在我们的研究中，使用了多种富含酚类化合物的材料，以便通过理化方法（例如溶剂萃取，通过膜过滤，在树脂上的吸附/解吸和真空蒸馏）分离酚类成分和最大程度的缩合。测试的材料是酿酒厂的固体废物，可可残留物，橄榄叶等。处理的第一步是使用最初优化的水-乙醇溶液萃取酚类成分。然后，通过超滤膜，纳滤和反渗透对提取物进行连续的膜过滤，以基于其分子量分离所含化合物。为了除去分子量与苯酚相似的非极性化合物，开发了在特定树脂上的吸附/解吸方法，以便最终获得富含酚类化合物的乙醇溶液。最后，在低温下通过真空蒸发除去乙醇。在本工作中详细说明了橄榄叶酚的纯化。最终获得的浓缩物是富含酚的浓缩物，并包含98 g / L没食子酸当量的酚。这种技术