This review discusses the functional polymer materials effect on the cell adhesion. The applied polymer materials for the cell adhesion purpose was prepared based on organic fibers and biocompatible hydrogel. On the other hand, the active peptides are incorporated into the polymer materials substrate via the cysteine-containing peptides and N-hydroxysuccinimide-active group. Cancer cells and normal cells were presented for the selective adhesion via the introduced polymer materials substrate containing active peptides including Arginine–Glycine-Aspartic and Isoleucine-Lysine–Valine-Alanine–Valine sequence peptides. This selectivity is revealed by a significant cooperativity between specific and non-specific cell adhesion. This study is of a great impact for the design of the polymeric structures for cell attachment.

这篇评论讨论了功能聚合物材料对细胞粘附的影响。基于有机纤维和生物相容性水凝胶，制备了用于细胞粘附目的的聚合物材料。另一方面，活性肽通过含半胱氨酸的肽和N被掺入聚合物材料的底物中-羟基琥珀酰亚胺活性基团。癌细胞和正常细胞通过引入的包含活性肽（包括精氨酸-甘氨酸-天冬氨酸和异亮氨酸-赖氨酸-缬氨酸-丙氨酸-缬氨酸序列肽）的聚合物材料底物进行选择性粘附。通过特异性和非特异性细胞粘附之间的显着协同作用揭示了这种选择性。这项研究对用于细胞附着的聚合物结构的设计具有重大影响。