Chemical modification of surfaces is recognized as efficient strategies to prevent bacterial contamination and the associated infection. Herein, a novel ionic liquid derivative 1‐(((4‐benzoylbenzoyl)oxy)methyl)‐3‐methyl‐1H‐imidazol‐3‐ium bromide (BMI) containing benzophenone moieties is developed to act as both a photoreactive cross‐linker and an antibacterial agent. BMI can rapidly and efficiently form a “smart” antibacterial film on a variety of substrate surfaces in 2 min under mild UV irradiation. The modified surfaces show highly antibacterial activity, achieving more than 99% bacterial killing efficiency against Gram‐positive Staphylococcus aureus and Gram‐negative Escherichia coli using live/dead staining methods. In addition, the BMI‐modified surfaces can release ≈97% of the killed bacteria via ion‐exchange of hexametaphosphate (PP⁶⁻) anions and can regenerate bactericidal properties over three cycles. Moreover, in vitro cytocompatibility tests indicate that the BMI‐modified surfaces have good biocompatibility. Thus, it can be concluded that cross‐linked BMI layers provide a practical and convenient approach for the fabrication of “smart” antibacterial surfaces.

中文翻译：

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通过一步光交联建立的智能抗菌表面

表面化学修饰被认为是防止细菌污染和相关感染的有效策略。本文中，开发了一种新型的含二苯甲酮部分的离子液体衍生物1-（（（（4-苯甲酰基苯甲酰基）氧基）甲基）-3-甲基-1 H-咪唑-3-溴化铵（BMI）。接头和抗菌剂。在轻微的紫外线照射下，BMI可以在2分钟内快速有效地在各种基材表面上形成“智能”抗菌膜。改性后的表面显示出很高的抗菌活性，对革兰氏阳性金黄色葡萄球菌和革兰氏阴性大肠杆菌的杀灭效率达到99％以上使用活/死染色方法。此外，经BMI改性的表面可通过六偏磷酸根（PP ⁶⁻）阴离子的离子交换释放约97％的被杀死细菌，并可以在三个周期内再生杀菌特性。此外，体外细胞相容性测试表明，经BMI修饰的表面具有良好的生物相容性。因此，可以得出结论，交联的BMI层为“智能”抗菌表面的制造提供了一种实用且方便的方法。