The progression of life in all forms is not only dependent on agricultural and food security but also on the soil characteristics. The dynamic nature of soil is a direct manifestation of soil microbes, bio-mineralization, and synergistic co-evolution with plants. With the increase in world’s population the demand for agriculture yield has increased tremendously and thereby leading to large scale production of chemical fertilizers. Since the use of fertilizers and pesticides in the agricultural fields have caused degradation of soil quality and fertility, thus the expansion of agricultural land with fertile soil is near impossible, hence researchers and scientists have sifted their attention for a safer and productive means of agricultural practices. Plant growth promoting rhizobacteria (PGPR) has been functioning as a co-evolution between plants and microbes showing antagonistic and synergistic interactions with microorganisms and the soil. Microbial revitalization using plant growth promoters had been achieved through direct and indirect approaches like bio-fertilization, invigorating root growth, rhizoremediation, disease resistance etc. Although, there are a wide variety of PGPR and its allies, their role and usages for sustainable agriculture remains controversial and restricted. There is also variability in the performance of PGPR that may be due to various environmental factors that might affect their growth and proliferation in the plants. These gaps and limitations can be addressed through use of modern approaches and techniques such as nano-encapsulation and micro-encapsulation along with exploring multidisciplinary research that combines applications in biotechnology, nanotechnology, agro biotechnology, chemical engineering and material science and bringing together different ecological and functional biological approaches to provide new formulations and opportunities with immense potential.

各种形式的生命发展不仅取决于农业和粮食安全，还取决于土壤的特性。土壤的动态性质是土壤微生物，生物矿化以及与植物协同协同进化的直接体现。随着世界人口的增加，对农业产量的需求已大大增加，从而导致了化肥的大规模生产。由于在农田中使用化肥和杀虫剂导致土壤质量和肥力下降，因此用肥沃的土壤扩大农田几乎是不可能的，因此，研究人员和科学家已将他们的注意力吸引到了一种更安全，生产性更高的农业实践手段上。促进植物生长的根际细菌（PGPR）一直作为植物与微生物之间的共同进化，表现出与微生物和土壤的拮抗和协同相互作用。使用植物生长促进剂进行的微生物活化已经通过直接和间接的方法来实现，例如生物施肥，促进根系生长，根茎修复，抗病性等。尽管PGPR及其盟友种类繁多，但它们在可持续农业中的作用和用途仍然存在有争议和受限制的。PGPR的性能也存在差异，这可能是由于各种环境因素可能会影响其在植物中的生长和繁殖。