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Aptamers in Bordeaux 2017: An exceptional “millésime”
Biochimie ( IF 3.3 ) Pub Date : 2017-11-24 , DOI: 10.1016/j.biochi.2017.11.015
Jean-Jacques Toulmé , Laurent Azéma , Fabien Darfeuille , Eric Dausse , Guillaume Durand , Olivier Paurelle

About 150 participants attended the symposium organised at the Palais de la Bourse in Bordeaux, France on September 22–23, 2017. Thirty speakers from all over the world delivered lectures covering selection processes, aptamer chemistry and innovative applications of these powerful tools that display major advantages over antibodies. Beyond the remarkable science presented, lively discussion and fruitful exchange between participants made this meeting a great success. A series of lectures were focused on synthetic biology (riboswitches, new synthetic base pairs, mutated polymerases). Innovative selection procedures including functional screening of oligonucleotide pools were described. Examples of aptasensors for the detection of pathogens were reported. The potential of aptamers for the diagnostic and the treatment of diseases was also presented. Brief summaries of the lectures presented during the symposium are given in this report. The third edition of this symposium will take place in Boulder, Colorado in Summer 2018 (information available at http://www.aptamers-in-bordeaux.com/).



中文翻译:

2017年波尔多适配子:非凡的“millésime”

大约有150名与会者参加了在巴黎证券交易所宫举办的专题讨论会2017年9月22日至23日在法国波尔多举行。来自世界各地的30位演讲者讲授了有关选择过程,适体化学和这些强大工具的创新应用的讲座,这些工具展现了超过抗体的主要优势。除了出色的科学表现之外,与会人员之间的热烈讨论和富有成果的交流使这次会议取得了巨大成功。一系列关于合成生物学的讲座(核糖开关,新的合成碱基对,突变的聚合酶)。描述了包括寡核苷酸池功能筛选在内的创新选择程序。报告了用于检测病原体的适体传感器的实例。还介绍了适体在疾病的诊断和治疗中的潜力。本报告介绍了座谈会期间演讲的简短摘要。该研讨会的第三版将于2018年夏季在科罗拉多州的博尔德举行(相关信息可在http://www.aptamers-in-bordeaux.com/上获得)。

更新日期:2017-11-24
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