Additive manufacturing (AM) is driving a paradigm shift in the way chromatographic and membrane materials will be made and used in the future for down-stream processing of bioproducts. Progress with prototypes already indicates that these ‘made-on-demand’ precision materials have broad scope and utility, initially targeted to applications with high value products, such as biopharmaceuticals, specialty proteins and stem cells. On further optimisation and scale-up, the advantages provided by novel AM-derived separation media and associated containment modules should rapidly filter down to many areas of analysis and process scale use with lower value commodity bio-based chemicals and biologicals.

增材制造（AM）正在推动色谱和膜材料的制造方式转变，并在未来用于生物产品的下游加工。原型的发展已经表明，这些“按需制造”的精密材料具有广泛的范围和实用性，最初瞄准的是具有高价值产品的应用，例如生物制药，特种蛋白质和干细胞。在进一步优化和扩大规模时，新型AM衍生的分离介质和相关容纳模块所提供的优势应迅速过滤到分析和工艺规模较小的许多领域，并使用价值较低的商品生物基化学品和生物制剂。