Heterocyclic systems are not only prevalent in an extensive number of natural products and artificial compounds but also used as building blocks in organic synthesis. Over 90% of new drugs contain at least one heterocyclic fragment in their structures. Therefore, the development of new one-pot methods for the synthesis of this important family of organic compounds that benefit from inexpensive, simple, and readily available starting materials continues to be a target of intense interest. Among recent reported synthetic methods, the chemical fixation of carbon dioxide onto organic compounds are one of the most interesting and promising synthetic procedures from the viewpoint of green and sustainable chemistry. Along this line, chemical fixation of CO₂ onto o-alkynylanilines has emerged over the past five years as a powerful and novel strategy to the synthesis of a variety of biologically important heterocyclic systems. In this mini review, we highlight the advances in this chemistry, with special emphasis on mechanistic aspects of the reactions.

杂环系统不仅广泛存在于多种天然产物和人工化合物中，而且还用作有机合成的基础。超过90％的新药在其结构中至少包含一个杂环片段。因此，开发新的一锅法来合成这种重要的有机化合物家族，这些方法得益于廉价，简单和易于获得的起始原料，仍然是人们强烈关注的目标。从绿色和可持续化学的观点来看，在最近报道的合成方法中，将二氧化碳化学固定在有机化合物上是最有趣和最有前途的合成方法之一。沿着这条线，将CO ₂化学固定在o上-炔基苯胺在过去五年中作为合成各种生物学上重要的杂环系统的有力且新颖的策略而出现。在本篇微型综述中，我们着重介绍了该化学的进展，特别着重于反应的机理方面。