Inhibition of Bacterial Adhesion on Nanotextured Stainless Steel 316L by Electrochemical Etching,ACS Biomaterials Science & Engineering

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Inhibition of Bacterial Adhesion on Nanotextured Stainless Steel 316L by Electrochemical Etching
ACS Biomaterials Science & Engineering ( IF 5.4 ) Pub Date : 2017-12-12 00:00:00 , DOI: 10.1021/acsbiomaterials.7b00544
Yeongseon Jang ₁ , Won Tae Choi _{1,

2} , Christopher T Johnson ₃ , Andrés J García ₄ , Preet M Singh ₂ , Victor Breedveld ₁ , Dennis W Hess ₁ , Julie A Champion ₁

Affiliation

Bacterial adhesion to stainless steel 316L (SS316L), which is an alloy typically used in many medical devices and food processing equipment, can cause serious infections along with substantial healthcare costs. This work demonstrates that nanotextured SS316L surfaces produced by electrochemical etching effectively inhibit bacterial adhesion of both Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus, but exhibit cytocompatibility and no toxicity toward mammalian cells in vitro. Additionally, the electrochemical surface modification on SS316L results in formation of superior passive layer at the surface, improving corrosion resistance. The nanotextured SS316L offers significant potential for medical applications based on the surface structure-induced reduction of bacterial adhesion without use of antibiotic or chemical modifications while providing cytocompatibility and corrosion resistance in physiological conditions.

中文翻译：

电化学刻蚀抑制纳米纹理不锈钢316L细菌粘附

不锈钢 316L (SS316L) 是一种通常用于许多医疗设备和食品加工设备的合金，细菌粘附在不锈钢 316L (SS316L) 上可能会导致严重感染以及巨额医疗费用。这项工作表明，通过电化学蚀刻产生的纳米纹理SS316L表面可以有效抑制革兰氏阴性大肠杆菌和革兰氏阳性金黄色葡萄球菌的细菌粘附，但在体外表现出细胞相容性并且对哺乳动物细胞无毒性。此外，SS316L 的电化学表面改性可在表面形成优异的钝化层，从而提高耐腐蚀性。纳米纹理 SS316L 具有显着的医疗应用潜力，其基于表面结构诱导的细菌粘附减少，无需使用抗生素或化学修饰，同时在生理条件下提供细胞相容性和耐腐蚀性。

更新日期：2017-12-12

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