Bacterial adhesion to stainless steel 316L (SS316L), which is an alloy typically used in many medical devices and food processing equipment, can cause serious infections along with substantial healthcare costs. This work demonstrates that nanotextured SS316L surfaces produced by electrochemical etching effectively inhibit bacterial adhesion of both Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus, but exhibit cytocompatibility and no toxicity toward mammalian cells in vitro. Additionally, the electrochemical surface modification on SS316L results in formation of superior passive layer at the surface, improving corrosion resistance. The nanotextured SS316L offers significant potential for medical applications based on the surface structure-induced reduction of bacterial adhesion without use of antibiotic or chemical modifications while providing cytocompatibility and corrosion resistance in physiological conditions.

中文翻译：

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电化学腐蚀抑制纳米织构不锈钢316L上的细菌粘附

细菌对不锈钢316L（SS316L）的粘附性是一种通常在许多医疗设备和食品加工设备中使用的合金，会导致严重的感染以及大量的医疗费用。这项工作表明，通过电化学蚀刻产生的纳米织构SS316L表面可有效抑制革兰氏阴性大肠杆菌和革兰氏阳性金黄色葡萄球菌的细菌粘附，但在体外表现出细胞相容性且对哺乳动物细胞无毒性。此外，SS316L上的电化学表面改性可在表面形成优异的钝化层，从而提高了耐腐蚀性。纳米结构的SS316L基于表面结构诱导的细菌粘附减少而无需使用抗生素或化学修饰，同时在生理条件下提供细胞相容性和耐腐蚀性，因此具有巨大的医疗应用潜力。