An efficient and easy protocol for promoting a C → N acyl transfer reaction in diverse enantiopure densely substituted pyrrolidine 2,2-dicarboxylates was performed, yielding the corresponding proline ester derivatives with yields in the range of 68–99% and total diastereoselection (dr > 95 : 5 in all cases). The substitution patterns both at C-3 and C-5 present in starting pyrrolidines as well as the viability of presenting different alkoxycarbonyl moieties have been evaluated observing good reaction performance in all cases.

中文翻译：

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在多取代的吡咯烷2，2-二羧酸酯中具有非对映选择性的C→N酰基重排。立体控制的稠密官能化脯氨酸的合成†

进行了有效而简便的方案，以促进各种对映纯的稠密取代的吡咯烷2，2-二羧酸酯中的C→N酰基转移反应，得到相应的脯氨酸酯衍生物，产率在68–99％范围内，总非对映选择性（dr> 95：5）。在所有情况下均观察到良好的反应性能，已评估了起始吡咯烷中存在的C-3和C-5处的取代方式以及呈现不同烷氧基羰基部分的可行性。