Convenient synthesis of 2-amino-3-(arylthio)indoles via the Rh-catalyzed reaction of 3-diazoindol-2-imines with thioesters†,Organic & Biomolecular Chemistry

当前位置： X-MOL 学术 › Org. Biomol. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Convenient synthesis of 2-amino-3-(arylthio)indoles via the Rh-catalyzed reaction of 3-diazoindol-2-imines with thioesters†
Organic & Biomolecular Chemistry ( IF 3.2 ) Pub Date : 2017-12-12 00:00:00 , DOI: 10.1039/c7ob02597a
Fanghui Ma _{1,

2,

3,

4} , Jing Qian _{1,

2,

3,

4} , Ping Lu _{1,

2,

3,

4} , Yanguang Wang _{1,

2,

3,

4}

Affiliation

2-Amino-3-(arylthio)indoles were conveniently synthesized via the Rh(II)-catalyzed C–S/N–C coupling reaction between 3-diazoindol-2-imines and thioesters. The products could be further oxidized to 2-amino-3-(arylsulfonyl)indoles by m-chloroperbenzoic acid and the N-sulfonyl group could be easily removed by reduction with SmI₂.

中文翻译：

方便的合成2-氨基-3-（芳基硫基）吲哚经由3- diazoindol -2-亚胺与硫酯上的Rh催化的反应†

通过Rh（II）催化的3-重氮吲哚-2-亚胺和硫代酸酯之间的C-S / N-C偶联反应可以方便地合成2-氨基-3-（芳硫基）吲哚。该产品可以被进一步氧化成2-氨基-3-（芳基磺酰基）吲哚由米氯过苯甲酸和Ñ磺酰基团可通过还原SMI容易地除去₂。

更新日期：2017-12-12

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南

全部期刊列表>>