We report biophysical studies of novel fluorine-labelled prokaryotic cell model membranes aiming to be used as NMR reporters for the study of biomolecule complexes. FTIR studies of F-DMPC/DMPC/DMPG tertiary mixtures were carried out at various fluorinated lipid/non-fluorinated lipid and PC/PG ratio. Preliminary solid-state static ¹⁹F- and ³¹P-NMR analyses are also reported and confirmed that those mixed bilayers could be used as bacterial model membranes to study interactions with biomolecules in NMR spectroscopy.

中文翻译：

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致力于在细菌模型膜中使用单氟化二肉豆蔻酰基磷脂酰胆碱作为¹⁹ F NMR报道分子

我们报道了新型的氟标记原核细胞模型膜的生物物理研究，该膜旨在用作生物分子复合物研究的NMR报道分子。F-DMPC / DMPC / DMPG三次混合物的FTIR研究是在各种氟化脂质/非氟化脂质和PC / PG比下进行的。初步的固态静态¹⁹ F -NMR和³¹ P-NMR分析也已报道，并证实这些混合的双层可用作细菌模型膜，以研究与NMR光谱中生物分子的相互作用。