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Small Bioactive Peptides for Biomaterials Design and Therapeutics
Chemical Reviews ( IF 62.1 ) Pub Date : 2017-12-11 00:00:00 , DOI: 10.1021/acs.chemrev.7b00522
I. W. Hamley 1
Affiliation  

This review is aimed to provide a concise yet extensive survey of key short bioactive peptide sequences for a range of applications ranging from biomaterials development to peptides with therapeutic uses. The following are considered: cell adhesion motifs, structural peptides, cell-penetrating and tumor-homing peptides, antimicrobial peptides, peptide hormones, growth factors and matrix metalloprotease substrates, neuropeptides, amyloid peptides, antioxidant peptides, peptide affinity tags, anticancer peptides, and others. This review provides a convenient resource, summarizing a broad range of important sequences with great utility as a resource concerning both small peptide drugs and also novel biofunctional peptide-based materials.

中文翻译:

用于生物材料设计和治疗的小型生物活性肽

这篇综述的目的是为关键的短生物活性肽序列提供简要而广泛的综述,以用于从生物材料开发到具有治疗用途的肽等一系列应用。考虑以下内容:细胞粘附基序,结构肽,细胞穿透肽和肿瘤归巢肽,抗菌肽,肽激素,生长因子和基质金属蛋白酶底物,神经肽,淀粉样肽,抗氧化剂肽,肽亲和标签,抗癌肽和其他。这篇综述提供了方便的资源,概述了重要序列的广泛范围,作为涉及小肽药物和新型基于生物功能肽的材料的资源,具有很大的实用性。
更新日期:2017-12-11
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