An indoloquinoline derivative induces dimerization of a parallel G‐quadruplex that lacks a 3′‐overhang sequence. Formed complexes exhibit a ligand sandwiched between the two blunt‐ended 3′‐tetrads. Formation of the sandwich‐type complex is supported by enhanced stacking energies but is also suggested to rely on additional ligand side‐chain interactions.

中文翻译：

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截断的平行MYC G四联体的配体诱导二聚化

吲哚喹啉衍生物可诱导缺少3'-突出端序列的平行G-四链体的二聚化。形成的复合物显示出一个夹在两个钝端3'-四联体之间的配体。三明治型复合物的形成得到增强的堆积能的支持，但也建议依赖于额外的配体侧链相互作用。